Study: Yale-developed mRNA vaccine offers superior protection against Omicron variants compared to Moderna, Pfizer vaccines Yale scientists have developed a new Omicron-specific mRNA vaccine that offers better protection over subvariants than standard mRNA vaccines, according to the university. The new vaccine, called Omnivax, had a better antibody response against the BA.1 and BA.2.12.1 Omicron subvariants in pre-immunized mice by 19-fold and eight-fold, respectively. “While standard mRNA vaccines still offer ... YahooNews

...

“While standard mRNA vaccines still offer protection against infection from new variants, their effectiveness wanes over time and was compromised due to immune escaping mutations in emerging variants,” said Sidi Chen, associate professor of genetics at Yale School of Medicine and senior author of both studies. “We wanted to see if we could develop variant-specific vaccines that offer additional protection against emerging subvariants.”...